HansaBioMed Life Sciences

Antibodies

Antibodies are an essential tool for basic research, development of diagnostic tests and therapeutics for human disease. Extracellular Vesicles (EVs), including exosomes, express antigens with 3D conformations and/or post-translational modifications that often differ from the cellular counterpart. For this reason, most of the antibodies currently available on the market fail to recognize EV-associated antigens with sufficient sensitivity and specificity. In collaboration with Exosomics Siena Spa, HBM has validated a list of polyclonal and monoclonal antibodies against common (CD63, CD81, ALIX) and disease- specific (cancer and neurodegenerative diseases) EV markers.

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