HansaBioMed Life Sciences
HansaBioMed Life Sciences OÜ

TFF-Flexi: Automated TFF-based EV isolation

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TFF-Flexi - Benchtop automation system adapted to TFF cartridges by HBM

  • Push-button automation
  • Scalable
  • Sterilizable
Standard
HBM-TFLEX
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Product Overview

Benchtop automation for TFF workflows. Adapted to all TFF cartridges by HBM, making it versatile in terms of use case scenarios and enabling easy scale up from 10ml up to 60L. The integrated software allows easy access to recommended protocols, modifications for customized workflows, and storage of data. With controlled pressure and flow speed, you can maximize the reproducibility of your EV production and minimize batch-to-batch variability.

 

Applications: Small/large EV isolation from various sources, concentration of isolated EV samples, buffer exchange, FBS depletion.

Compatible cartridges: TFF-Easy, TFF-EVs-S, TFF-EVs-L, TFF-MV
Biosource: Biofluids, cell conditioned media, plant extracts, bacteria, fungi
Operating volume: 10mL-60L
Sterilization: TFF cartridges come sterile, instrument can be autoclaved
Membrane rating: 15-1000kDa
Membrane types: Hollow fiber membranes
Membrane material: Polysulfone, polyethersulfone
Flow rate: 0.05-2 L/min

Concentration of diluted matrices such as cell media or urine prior to EV isolation

EV dialysis for changing buffer conditions

High efficiency of EV isolation if coupled with SEC columns.

Separation and recovery of large EVs and nanoparticles

Removal of small molecules and unbound dyes from solution containing EVs/exosomes and nanoparticles

Improving EV purity

EV isolation from biofluids and conditioned cell media

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